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The Effects of Tempeh Gembus, an Indonesian Fermented Food, on Lipid Profiles in Women with Hyperlipidemia

[ Vol. 16 , Issue. 1 ]

Author(s):

Diana Nur Afifah*, Nida Nabilah, Galuh Tamarasani Supraba, Syafira Noor Pratiwi, Nuryanto and Mohammad Sulchan   Pages 56 - 64 ( 9 )

Abstract:


Background: Hyperlipidemia is the major precursor of lipid-related diseases. Consumption of high fiber foods may decrease lipid profiles. The fiber content in tempeh gembus is three times higher than regular tempeh.

Objective: This study was conducted to investigate the effect of tempeh gembus on lipid profiles in women with hyperlipidemia.

Methods: This research used the quasi-experimental design with nonequivalent control group design. Subjects were 41 women with hyperlipidemia, classified into 3 groups: control group, treatment group 1 given 103 g/day tempeh gembus, and treatment group 2 given 206 g/day tempeh gembus for 14 days. All of the groups received nutrition education. Total cholesterol and HDL-C were determined by CHOD-PAP method, triglyceride determined by enzymatic GPO-PAP method after subjects had been fasting for approximately 10 hours. LDL-C was calculated by Friedewald equation.

Results: These results showed that consumption of tempeh gembus 103 g/day and 206 g/day decreased LDL-C 27.9% and 30.9% as well as decreased total cholesterol 17.7% and 19.8% respectively. However, HDL-C increased 3.91% and 8.79% and triglyceride increased 2.3% and 3.1%. Tempeh gembus given 206 g/day was more effective to decrease total cholesterol and LDL-C than 103 g/day.

Conclusion: Increasing tempeh gembus consumption in women with hyperlipidemia should be addressed to decrease LDL-C and total cholesterol.

Keywords:

Fiber, HDL-C, hyperlipidemia, LDL-C, Tempeh Gembus, total cholesterol, triglyceride.

Affiliation:

Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang, Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang

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