Farah Kenza Benattia* and Zoheir Arrar Pages 211 - 217 ( 7 )
Background: The prickly pear cactus or Nopal is a plant that is well adapted to arid and semi-arid climates like that of Algeria. It produces sweet nutritionally rich edible fruits, and it has been used in traditional folk medicine.
Objective: This study aimed to chemically characterize the cactus seed extracts by using different solvents, to optimize extraction parameters of bioactive compounds, and to evaluate in vitro their antioxidant activities by ferric reducing antioxidant power (FRAP), and 2,2-diphenyl-1-picrylhydrazyl (DPPH).
Methods: Two extraction methods were used (soxhlet, maceration); the active antioxidant, phenolic and flavonoids contents were determined using colorimetric method.
Results: The best extraction yields are recorded in the polar extracts with 31.5% as the highest percentage represented by the hydro-ethanolic extract. The same extract contains high rate of phenolic compound with 144.5 gallic acid mg/100 g DM followed by the aqueous extract 114.87 mg GAE/100 g. The radical scavenging activity, expressed as a function of IC50, equals 0.13, and 0.15 for hydroethanolic and aqueous extracts, respectively.
Conclusion: Cactus seeds could be a potential source of natural compounds and therapeutic agents which are useful in the prevention or treatment of diseases associated with oxidative stress.
Extact Etoh 50%, extraction solvent, medicinal plants, Opuntia ficus-indica, total polyphenols, cactus seeds.
Department of Chemistry, Laboratory of Organic Chemistry, Natural Products and Analysis (COSNA), University of Tlemcen, P.O. Box 119, Tlemcen 13000, Department of Chemistry, Laboratory of Organic Chemistry, Natural Products and Analysis (COSNA), University of Tlemcen, P.O. Box 119, Tlemcen 13000